The Human CD4 Monoclonal Antibody (FITC-conjugated) - RPA-T4 (AGEL0399) is a cutting-edge tool for immune system research, specifically targeting the CD4 protein that plays a pivotal role in T-cell function. This monoclonal antibody, labeled with FITC for fluorescence detection, has been meticulously developed for precise identification and analysis of CD4 expression in human samples.CD4, a crucial surface receptor on helper T cells, is instrumental in orchestrating and regulating immune responses. By binding specifically to CD4 molecules, this antibody allows for accurate visualization and quantification of CD4-positive cells in diverse experimental settings. Its compatibility with fluorescence-based techniques makes it a versatile choice for flow cytometry, immunofluorescence, and related applications in immunology and infectious disease research.
Moreover, the CD4 Monoclonal Antibody (FITC-conjugated) - RPA-T4 (AGEL0399) holds immense potential for investigations into HIV/AIDS, autoimmune diseases, and other conditions characterized by alterations in T-cell function. By unraveling the intricate mechanisms of CD4 biology, researchers can gain crucial insights into disease pathogenesis and therapeutic approaches aimed at modulating immune responses. Elevate your research endeavors with this high-quality antibody and unlock new avenues of discovery in the realm of immunology.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P01730
Gene ID:
920
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD4, also known as T4/Leu-3, is a 55 kD single-chain type I transmembrane glycoprotein and member of the immunoglobulin superfamily. It is expressed on most thymocytes, helper T cells, type II NKT cells, and monocytes/macrophages. CD4 is part of the TCR/CD3 complex, binds to β2 domain from the MHC class II molecule, and participates in TCR signal transduction. CD4 is the receptor of IL-16 and is a coreceptor for the human immunodeficiency virus (HIV) and human herpes virus 7 (HHV-7).