The Human CD4 Monoclonal Antibody Alexa Fluor 488 Conjugated (RPA-T4) is a cutting-edge tool for researchers studying the CD4 cell surface marker, which plays a pivotal role in the immune system. This specialized antibody, conjugated with Alexa Fluor 488 for fluorescent detection, offers high specificity and sensitivity in detecting CD4 expression in human samples.CD4 is a crucial component of the immune system, primarily found on helper T cells. By targeting the CD4 protein, researchers can gain valuable insights into immune response mechanisms, inflammatory processes, and various diseases.
The Alexa Fluor 488 conjugation allows for precise visualization and quantification of CD4-positive cells in flow cytometry, immunofluorescence, and other experimental procedures.With its robust performance and reliable results, the Human CD4 Monoclonal Antibody Alexa Fluor 488 Conjugated (RPA-T4) is an invaluable asset for studies in immunology, infectious diseases, and autoimmune disorders. Researchers can leverage this antibody to explore the role of CD4 in immune function, disease pathogenesis, and potential therapeutic interventions.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P01730
Gene ID:
920
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD4, also known as T4/Leu-3, is a 55 kD single-chain type I transmembrane glycoprotein and member of the immunoglobulin superfamily. It is expressed on most thymocytes, helper T cells, type II NKT cells, and monocytes/macrophages. CD4 is part of the TCR/CD3 complex, binds to β2 domain from the MHC class II molecule, and participates in TCR signal transduction. CD4 is the receptor of IL-16 and is a coreceptor for the human immunodeficiency virus (HIV) and human herpes virus 7 (HHV-7).