The Human CD4 Monoclonal Antibody AF647 Conjugated RPA-T4 (AGEL1389) is a cutting-edge tool for researchers studying the CD4 protein, a key player in immune function and T cell activation. This monoclonal antibody, conjugated with AF647 fluorophore, offers high specificity and sensitivity in detecting CD4 in human samples. Ideal for fluorescence microscopy and flow cytometry applications, this antibody enables precise visualization and quantification of CD4 expression in different cell populations. Its conjugation with AF647 enhances signal intensity, allowing for accurate identification and analysis of CD4-positive cells.The CD4 protein is crucial for the immune system's proper functioning, serving as a co-receptor for T cell activation and differentiation.
Research involving CD4 is essential for understanding immune responses, HIV/AIDS pathogenesis, autoimmune diseases, and immunotherapy efficacy. This antibody provides researchers with a reliable tool to investigate CD4-related processes and advance their knowledge in immunology and infectious diseases.Enhance your research capabilities with the Human CD4 Monoclonal Antibody AF647 Conjugated RPA-T4 (AGEL1389) and uncover new insights into the intricate mechanisms of immune regulation and T cell biology.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P01730
Gene ID:
920
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD4, also known as T4/Leu-3, is a 55 kD single-chain type I transmembrane glycoprotein and member of the immunoglobulin superfamily. It is expressed on most thymocytes, helper T cells, type II NKT cells, and monocytes/macrophages. CD4 is part of the TCR/CD3 complex, binds to β2 domain from the MHC class II molecule, and participates in TCR signal transduction. CD4 is the receptor of IL-16 and is a coreceptor for the human immunodeficiency virus (HIV) and human herpes virus 7 (HHV-7).