Human CD3E Polyclonal Antibody (CAB24879)
- SKU:
- CAB24879
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- IF
Frequently bought together:
Description
Product Name: | Human CD3E Polyclonal Antibody |
SKU: | CAB24879 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-126 of human CD3E(NP_000724.1). |
Sequence: | DGNE EMGG ITQT PYKV SISG TTVI LTCP QYPG SEIL WQHN DKNI GGDE DDKN IGSD EDHL SLKE FSEL EQSG YYVC YPRG SKPE DANF YLYL RARV CENC MEMD |
Tested Applications: | WB IF/ICC |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | CD3E; IMD18; T3E; TCRE; CD3e molecule; Human CD3E |
Positive Sample: | MOLT-4,Jurkat,Jurkat |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Single-pass type I membrane protein. |
Calculated MW: | 23kDa |
Observed MW: | 23kDa/ |
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
Purification Method: | Affinity purification |
Gene ID: | 916 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |