The Human CD38 Monoclonal Antibody (PE/Cyanine7 Conjugated) - HIT2 (AGEL0990) is a powerful tool designed for research applications involving CD38, a cell surface glycoprotein involved in immune response modulation and cellular signaling. This monoclonal antibody, conjugated with PE/Cyanine7 for enhanced detection, is specifically raised against human CD38 and is highly sensitive and specific in its binding.CD38 is known to play a crucial role in immune regulation, cell activation, and signaling pathways, making it a key molecule of interest in immunology, cancer research, and autoimmune disease studies. By targeting CD38 with this monoclonal antibody, researchers can effectively detect and analyze CD38 expression in various cell types, providing valuable insights into its function and potential therapeutic implications.
With its reliable performance in techniques such as flow cytometry and immunofluorescence, the Human CD38 Monoclonal Antibody (PE/Cyanine7 Conjugated) - HIT2 (AGEL0990) is an essential tool for investigating the role of CD38 in immune responses, inflammatory processes, and disease pathogenesis, leading to a better understanding of its molecular function and its relevance in various biological contexts.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P28907
Gene ID:
952
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD38 is a 45 kD type II transmembrane glycoprotein also known as T10. It is an ADP-ribosyl hydrolase expressed at variable levels on hematopoietic cells and in some non-hematopoietic tissues (such as brain, muscles, and kidney). In humans, it is expressed at high levels on plasma cells and activated T and B cells. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, adhesion, and the metabolism of cADPR and NAADP. CD31 is the ligand of CD38.