The Human CD38 Monoclonal Antibody (PE Conjugated, HIT2, AGEL0986) from AssayGenie is a powerful tool for studying CD38, a transmembrane glycoprotein involved in cell signaling and immune responses. This monoclonal antibody, conjugated with PE for easy detection, is specifically designed for use in flow cytometry applications to analyze and quantify CD38 expression on human cells.CD38 is a multifunctional ectoenzyme with roles in calcium signaling, cell adhesion, and immune regulation. It is implicated in various physiological and pathological processes, including immune activation, inflammation, and cancer progression. By targeting CD38 with this specific monoclonal antibody, researchers can gain insights into the expression levels and distribution of CD38 on different cell populations, aiding in the investigation of its function in health and disease.
The Human CD38 Monoclonal Antibody (PE Conjugated, HIT2, AGEL0986) is highly sensitive and specific, allowing for accurate and reliable detection of CD38 in diverse biological samples. It is a valuable tool for immunology, oncology, and cell biology research, providing researchers with the means to explore the role of CD38 in various cellular processes and disease states. Explore the functions of CD38 with confidence using this high-quality antibody from AssayGenie.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P28907
Gene ID:
952
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD38 is a 45 kD type II transmembrane glycoprotein also known as T10. It is an ADP-ribosyl hydrolase expressed at variable levels on hematopoietic cells and in some non-hematopoietic tissues (such as brain, muscles, and kidney). In humans, it is expressed at high levels on plasma cells and activated T and B cells. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, adhesion, and the metabolism of cADPR and NAADP. CD31 is the ligand of CD38.