The Human CD38 Monoclonal Antibody (Biotin Conjugated, HIT2) is a powerful tool for researchers studying CD38, a transmembrane glycoprotein involved in various cellular processes, including immune regulation and cell signaling. This monoclonal antibody, labeled with biotin for versatile detection methods, is highly specific to the human CD38 protein and is suitable for a range of applications in immunology, oncology, and cell biology.CD38 is known for its role in immune responses, cell adhesion, and calcium signaling, making it a key target for investigating immune function and disease mechanisms. This antibody enables the precise identification and localization of CD38 expression in human samples, facilitating detailed analysis and characterization of CD38-expressing cells in research settings.
Ideal for techniques such as flow cytometry, immunofluorescence, and immunohistochemistry, the Human CD38 Monoclonal Antibody (Biotin Conjugated, HIT2) offers reliable and reproducible results for researchers interested in exploring the involvement of CD38 in various physiological and pathological processes. Enhance your studies in immunology and cancer research with this valuable antibody reagent from Assay Genie.
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:
P28907
Gene ID:
952
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD38 is a 45 kD type II transmembrane glycoprotein also known as T10. It is an ADP-ribosyl hydrolase expressed at variable levels on hematopoietic cells and in some non-hematopoietic tissues (such as brain, muscles, and kidney). In humans, it is expressed at high levels on plasma cells and activated T and B cells. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, adhesion, and the metabolism of cADPR and NAADP. CD31 is the ligand of CD38.