The Human CD38 Monoclonal Antibody (Alexa Fluor 488 Conjugated, HIT2) - AGEL0248 is an essential tool for researchers investigating CD38, a transmembrane glycoprotein involved in various cellular processes such as cell adhesion, signaling, and calcium signaling. This antibody, a monoclonal clone that specifically targets human CD38, is conjugated with Alexa Fluor 488 for fluorescent detection applications.CD38 is a multifunctional protein known for its roles in immune regulation, cell activation, and differentiation. It is expressed on a variety of cell types, including immune cells, endothelial cells, and neurons. The CD38 Monoclonal Antibody offers high specificity and sensitivity in detecting CD38 expression, providing valuable insights into its localization and function within different cell populations.Researchers studying immunology, oncology, and neurobiology can benefit from the CD38 Monoclonal Antibody for visualizing and quantifying CD38 levels in different experimental contexts.
Whether investigating immune cell function, tumor microenvironment dynamics, or neuroinflammation processes, this antibody enables precise and reliable detection of CD38, facilitating the elucidation of its impact on disease progression and therapeutic targeting strategies.In summary, the Human CD38 Monoclonal Antibody (Alexa Fluor 488 Conjugated, HIT2) - AGEL0248 is a powerful research tool for studying the biology of CD38 and its implications in various physiological and pathological conditions. Its fluorescence-conjugated format enhances its utility in imaging and flow cytometry applications, offering researchers a comprehensive solution for investigating CD38-mediated processes in health and disease.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P28907
Gene ID:
952
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD38 is a 45 kD type II transmembrane glycoprotein also known as T10. It is an ADP-ribosyl hydrolase expressed at variable levels on hematopoietic cells and in some non-hematopoietic tissues (such as brain, muscles, and kidney). In humans, it is expressed at high levels on plasma cells and activated T and B cells. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, adhesion, and the metabolism of cADPR and NAADP. CD31 is the ligand of CD38.