The Human CD36 Monoclonal Antibody (APC Conjugated) is an essential tool for researchers studying CD36, a cell surface receptor involved in lipid metabolism and immune responses. This monoclonal antibody, labeled with APC for convenient detection, specifically targets human CD36 and is validated for use in flow cytometry applications.CD36, a multifunctional scavenger receptor, plays a pivotal role in various biological processes, including lipid uptake, inflammation, and immune response modulation. Its involvement in lipid metabolism has made it a focal point in studies related to atherosclerosis, obesity, and metabolic disorders.
Additionally, CD36's role in immune regulation underscores its relevance in research on infectious diseases, autoimmune conditions, and inflammatory disorders.By utilizing the Human CD36 Monoclonal Antibody (APC Conjugated), researchers can accurately detect and analyze CD36 expression in diverse cell types, offering valuable insights into the molecular mechanisms underlying lipid metabolism and immune regulation. This antibody is a valuable asset for investigations in the fields of immunology, metabolism, and cardiovascular health.
Product Title:
APC Anti-Human CD36 Antibody [5-271]
SKU:
AGEL1824
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
5-271
Synonyms:
GP3B;GP4;GPIV;GPIIIB;PAS-4;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG2a, κ
Isotype Control:
APC Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:
Liquid
Conjugation:
APC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P16671
Gene ID:
948
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD36 is an 85 kD integral membrane glycoprotein, also known as GPIIIb, or GPIV. It is expressed on various epithelial and endothelial cells as well as erythrocytes, platelets, macrophages/monocytes and some macrophage-derived dendritic cells. CD36 functions as a scavenger receptor, binding thrombospondin, long chain fatty acids, oxidized LDL, collagen type I, IV, and V as well as apoptotic cells. The 5-271 antibody has been reported to be useful for flow cytometry.