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PE/Cyanine5 Anti-Human CD35 Antibody [E11] (AGEL1013)

SKU:
AGEL1013
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
€209 - €709
Frequently bought together:

Description

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PE/Cyanine5 Anti-Human CD35 Antibody [E11]

The Human CD35 Monoclonal Antibody (PE/Cyanine5 Conjugated) E11-AGEL1013 is a cutting-edge tool designed for research involving CD35, a crucial cell surface receptor involved in immune function. This antibody, a monoclonal antibody with PE/Cyanine5 conjugation, is highly specific to human samples and is validated for use in flow cytometry applications. By targeting the CD35 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it an invaluable asset for studies in immunology and related fields.CD35, also known as complement receptor 1 (CR1), plays a pivotal role in the immune system by regulating the activation of complement pathways and impacting immune response dynamics.

Its involvement in immune complex clearance and modulation of inflammatory processes underscores its importance in understanding diseases such as autoimmune disorders, infectious diseases, and inflammatory conditions. Research on CD35 is vital for developing targeted therapeutics that can manipulate immune responses effectively in various disease contexts.Equip your research with the precision and reliability of the Human CD35 Monoclonal Antibody (PE/Cyanine5 Conjugated) E11-AGEL1013 to delve deeper into the intricate mechanisms of immune regulation and pave the way for innovative therapeutic interventions.

Product Title:PE/Cyanine5 Anti-Human CD35 Antibody [E11]
SKU:AGEL1013
Size:20 Tests, 100 Tests, 200 Tests
Clone No:E11
Synonyms:Complement receptor type 1;CR1;C3b/C4b receptor;CD35;CR1;C3BR;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P17927
Gene ID:1378
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD35 is a type I single chain of glycoprotein, also known as C3b/C4b receptor, Complement Receptor type 1 or CR1. Four molecular weight allotypes (160kD, 190kD, 220kD, and 250kD) have been described. CD35 is expressed on granulocytes, monocytes, B cells, erythrocytes, and follicular dendritic cells, as well as subsets of NK and T cells. CD35 binds complement C3b, C4b, or iC3, and iC4, and plays important roles in both innate and adoptive immune response via mediating phagocytosis by granulocytes and monocytes. CD35 has also been reported to inhibit T-cell proliferation.

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