The Human CD35 Monoclonal Antibody (PE Conjugated) E11 (AGEL1011) from Assay Genie is a powerful tool for research involving CD35, a cell surface molecule with essential roles in the immune system. This monoclonal antibody, conjugated with PE for easy detection, is specifically designed for use with human samples and is validated for a variety of applications.In studies related to immunology, hematology, and inflammatory conditions, the CD35 antibody can facilitate the detection and analysis of CD35 protein expression in different cell types. By targeting CD35, researchers can gain valuable insights into its functions and interactions, aiding in the understanding of immune responses and potential therapeutic interventions.
The versatility and specificity of the Human CD35 Monoclonal Antibody (PE Conjugated) E11 (AGEL1011) make it an essential tool for investigations into immune system dynamics, complement activation, and related pathways. Researchers looking to explore the intricacies of CD35 biology in human samples will find this antibody to be a reliable and effective resource for their studies.
Product Title:
PE Anti-Human CD35 Antibody [E11]
SKU:
AGEL1011
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
E11
Synonyms:
Complement receptor type 1;CR1;C3b/C4b receptor;CD35;CR1;C3BR;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG1, κ
Isotype Control:
PE Mouse IgG1, κ Isotype Control[MOPC-21]
Form:
Liquid
Conjugation:
PE
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P17927
Gene ID:
1378
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD35 is a type I single chain of glycoprotein, also known as C3b/C4b receptor, Complement Receptor type 1 or CR1. Four molecular weight allotypes (160kD, 190kD, 220kD, and 250kD) have been described. CD35 is expressed on granulocytes, monocytes, B cells, erythrocytes, and follicular dendritic cells, as well as subsets of NK and T cells. CD35 binds complement C3b, C4b, or iC3, and iC4, and plays important roles in both innate and adoptive immune response via mediating phagocytosis by granulocytes and monocytes. CD35 has also been reported to inhibit T-cell proliferation.