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GenieFluor 488 Anti-Human CD35 Antibody [E11] (AGEL1015)

SKU:
AGEL1015
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2a,k
Clone:
E11
Conjugation:
AF 488
€209 - €709
Frequently bought together:

Description

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GenieFluor 488 Anti-Human CD35 Antibody [E11]

The Human CD35 Monoclonal Antibody (AF488 conjugated) is a cutting-edge tool designed for researchers working with CD35, a crucial cell surface protein involved in immune response and regulation. This monoclonal antibody, labeled with AF488 for fluorescence detection, offers high specificity and sensitivity for detecting CD35 in human samples across a range of experimental applications.CD35, also known as complement receptor 1 (CR1), plays a pivotal role in the complement system, a part of the immune response that helps clear pathogens and damaged cells. By binding specifically to CD35, this antibody enables precise identification and analysis of CD35 expression in various cell types, making it an ideal asset for immunology research, autoimmune disease studies, and investigations into inflammatory conditions.

Researchers utilizing the Human CD35 Monoclonal Antibody (AF488 conjugated) can gain a deeper understanding of the immune modulation mechanisms involving CD35, potentially uncovering new insights into immune-related disorders such as autoimmune diseases, infections, and inflammatory conditions. The antibody's reliable performance in fluorescence-based assays makes it an invaluable tool for exploring the functions and roles of CD35 in health and disease contexts.

Product Title:GenieFluor 488 Anti-Human CD35 Antibody [E11]
SKU:AGEL1015
Size:20 Tests, 100 Tests, 200 Tests
Clone No:E11
Synonyms:Complement receptor type 1;CR1;C3b/C4b receptor;CD35;CR1;C3BR;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Genie Fluor 488 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P17927
Gene ID:1378
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD35 is a type I single chain of glycoprotein, also known as C3b/C4b receptor, Complement Receptor type 1 or CR1. Four molecular weight allotypes (160kD, 190kD, 220kD, and 250kD) have been described. CD35 is expressed on granulocytes, monocytes, B cells, erythrocytes, and follicular dendritic cells, as well as subsets of NK and T cells. CD35 binds complement C3b, C4b, or iC3, and iC4, and plays important roles in both innate and adoptive immune response via mediating phagocytosis by granulocytes and monocytes. CD35 has also been reported to inhibit T-cell proliferation.

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