The Human CD34 Monoclonal Antibody FITC Conjugated (AGEL1733) is a specialized tool for research involving CD34, a transmembrane glycoprotein present on hematopoietic stem cells and endothelial cells. This unique antibody, conjugated with FITC for fluorescence detection, is specifically designed for flow cytometry applications in the analysis of CD34 expression in human samples.CD34 is a well-known marker for hematopoietic stem and progenitor cells, playing a crucial role in cell adhesion and signal transduction processes. The CD34 Monoclonal Antibody FITC Conjugated (AGEL1733) enables precise detection and quantification of CD34 expression, facilitating the identification and characterization of hematopoietic stem and progenitor cells in various research settings.
With its high specificity and sensitivity, this antibody is an essential tool for studies in stem cell biology, regenerative medicine, and hematopoiesis research. By targeting CD34-expressing cells, researchers can gain valuable insights into cell differentiation, proliferation, and mobilization processes, paving the way for advancements in therapeutic strategies for diseases such as leukemia, lymphoma, and other hematological disorders.Choose the Human CD34 Monoclonal Antibody FITC Conjugated (AGEL1733) for accurate and reliable flow cytometry analysis of CD34 expression, accelerating your research efforts in the field of hematopoietic stem cell biology and beyond.
Product Title:
FITC Anti-Human CD34 Antibody [581]
SKU:
AGEL1733
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
581
Synonyms:
Gp105-120; My10;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG1, κ
Isotype Control:
FITC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:
Liquid
Conjugation:
FITC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P28906
Gene ID:
947
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD34, also known as gp105-120, is a type I monomeric sialomucin-like glycophosphoprotein with an approximate molecular weight of 105-120 kD. Selectively expressed on the majority of hematopoietic stem/progenitor cells, bone marrow stromal cells, capillary endothelial cells, embryonic fibroblasts, and some nervous tissue, CD34 is a commonly used marker to identify human hematopoietic stem/progenitor cells. According to the differential sensitivity to enzymatic cleavage, four groups of epitopes of CD34 have been described. CD34 mediates cell adhesion and lymphocytes homing through binding to L-selectin and E-selectin ligands.