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PE Anti-Human CD32 Antibody [IV-3] (AGEL1074)

SKU:
AGEL1074
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
€189 - €629
Frequently bought together:

Description

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PE Anti-Human CD32 Antibody [IV-3]

The Human CD32 Monoclonal Antibody (PE-Conjugated, IV.3) is a specialized tool designed for research applications involving the CD32 protein, also known as Fc gamma receptor IIa. This monoclonal antibody, labeled with phycoerythrin (PE), offers high specificity and sensitivity in detecting and analyzing CD32 expression in human samples. CD32 is a cell surface receptor that plays a crucial role in mediating immune responses, particularly in the context of antibody-dependent cellular cytotoxicity (ADCC) and phagocytosis. By targeting CD32, researchers can gain insights into its function in immune regulation and its involvement in various immune-related processes.

The PE conjugation of this monoclonal antibody allows for easy visualization and analysis of CD32 expression using flow cytometry and fluorescence microscopy techniques. Its application is particularly valuable in immunology research, infectious disease studies, and the development of novel therapeutic strategies targeting CD32-mediated pathways.By utilizing the Human CD32 Monoclonal Antibody (PE-Conjugated, IV.3), researchers can advance their understanding of CD32 biology and its implications in immune modulation, paving the way for potential advancements in immunotherapy, vaccine development, and immune-related disease treatments.

Product Title:PE Anti-Human CD32 Antibody [IV-3]
SKU:AGEL1074
Size:20 Tests, 100 Tests, 200 Tests
Clone No:IV-3
Synonyms:Low affinity immunoglobulin gamma Fc region receptor II-b;FCGR2B;IgG Fc receptor II-b;CDw32;Fc-gamma RII-b;Fc-gamma-RIIb;FcRII-b;CD32;FCG2; IGFR2;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2b, κ
Isotype Control:PE Mouse IgG2b, κ Isotype Control[MPC-11]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P31994
Gene ID:2212
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform).

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