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FITC Anti-Human CD32 Antibody [IV-3] (AGEL1073)

SKU:
AGEL1073
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
€189 - €629
Frequently bought together:

Description

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FITC Anti-Human CD32 Antibody [IV-3]

The Human CD32 Monoclonal Antibody FITC Conjugated (IV.3) is a specialized tool for researchers investigating CD32, a cell surface protein involved in immune responses. This monoclonal antibody, conjugated with FITC for fluorescence detection, is specifically designed for use in flow cytometry and immunofluorescence applications. CD32, also known as Fc gamma receptor II, plays a crucial role in the immune system by mediating various immune functions, including phagocytosis and antibody-dependent cellular cytotoxicity. By targeting CD32, researchers can gain insights into how immune cells interact with pathogens and how dysregulation of this receptor may contribute to autoimmune diseases and infections.

The FITC conjugation of this antibody allows for easy and sensitive detection of CD32 on cell surfaces, making it an essential tool for studies related to immunology, infectious diseases, and autoimmune disorders. With its proven specificity for human samples, this antibody is a valuable asset for investigating the complexities of immune responses and designing targeted therapeutic interventions.

Product Title:FITC Anti-Human CD32 Antibody [IV-3]
SKU:AGEL1073
Size:20 Tests, 100 Tests, 200 Tests
Clone No:IV-3
Synonyms:Low affinity immunoglobulin gamma Fc region receptor II-b;FCGR2B;IgG Fc receptor II-b;CDw32;Fc-gamma RII-b;Fc-gamma-RIIb;FcRII-b;CD32;FCG2; IGFR2;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2b, κ
Isotype Control:FITC Mouse IgG2b, κ Isotype Control[MPC-11]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P31994
Gene ID:2212
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform).

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