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Biotin Anti-Human CD32 Antibody [IV-3] (AGEL0292)

SKU:
AGEL0292
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2b
Clone:
IV-3
Conjugation:
Biotin
Applications:
FC
$179 - $395
Frequently bought together:

Description

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Biotin Anti-Human CD32 Antibody [IV-3]

The Human CD32 Monoclonal Antibody (Biotin Conjugated) IV.3 (AGEL0292) offered by AssayGenie is a cutting-edge tool for researchers studying the CD32 protein, a key player in immune response and inflammation regulation. This monoclonal antibody, conjugated with biotin for enhanced detection capabilities, specifically targets the CD32 protein in human samples. Validated for various applications, including immunohistochemistry and flow cytometry, this antibody enables precise detection and analysis of CD32 expression in different cell types, making it invaluable for studies in immunology, autoimmune disorders, and infectious diseases.

CD32, also known as Fc-gamma receptor II, is a crucial component of the immune system, mediating interactions between cells and antibodies. Understanding the role of CD32 is essential for unraveling immune responses in conditions such as autoimmune diseases, allergies, and infections. Researchers can utilize this antibody to delve into the intricate functions of CD32 and its involvement in immune pathways, paving the way for novel therapeutic strategies and diagnostic approaches in various disease settings.

Product Title:Biotin Anti-Human CD32 Antibody [IV-3]
SKU:AGEL0292
Size:25µg, 100µg
Clone No:IV-3
Synonyms:Low affinity immunoglobulin gamma Fc region receptor II-b;FCGR2B;IgG Fc receptor II-b;CDw32;Fc-gamma RII-b;Fc-gamma-RIIb;FcRII-b;CD32;FCG2; IGFR2;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2b, κ
Isotype Control:Biotin Mouse IgG2b, κ Isotype Control[MPC-11]
Form:Liquid
Conjugation:Biotin
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P31994
Gene ID:2212
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform).

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