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GenieFluor 488 Anti-Human CD32 Antibody [IV-3] (AGEL0293)

SKU:
AGEL0293
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2b
Clone:
IV-3
Conjugation:
AF 488
Applications:
FC
€259 - €889
Frequently bought together:

Description

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GenieFluor 488 Anti-Human CD32 Antibody [IV-3]

The Human CD32 Monoclonal Antibody (Alexa Fluor 488 Conjugated) (IV.3) is a powerful tool for researchers studying the CD32 protein, an important immune receptor involved in immune responses and cell signaling pathways. This monoclonal antibody, conjugated with Alexa Fluor 488 for fluorescent detection, specifically targets and binds to human CD32, allowing for precise visualization and analysis in various experimental setups.CD32, also known as Fc gamma receptor II, is a key player in immune regulation and inflammation, mediating the interaction between antibodies and immune cells. By targeting CD32 with this antibody, researchers can investigate its role in immune complex signaling, antibody-mediated cellular processes, and immune system dysfunctions.

This antibody is validated for use in techniques like flow cytometry, immunofluorescence, and immunohistochemistry, providing a versatile tool for studying CD32 expression and function in different cell types and tissues.The Human CD32 Monoclonal Antibody (Alexa Fluor 488 Conjugated) (IV.3) is essential for advancing research in immunology, infectious diseases, and autoimmune disorders. Its high specificity and sensitivity make it a valuable asset for scientists seeking to unravel the complexities of immune responses and develop targeted therapies for conditions where CD32 plays a crucial role. Discover new insights into immune regulation with this cutting-edge antibody and uncover the mysteries of CD32 biology in health and disease.

Product Title:GenieFluor 488 Anti-Human CD32 Antibody [IV-3]
SKU:AGEL0293
Size:20 Tests, 100 Tests, 200 Tests
Clone No:IV-3
Synonyms:Low affinity immunoglobulin gamma Fc region receptor II-b;FCGR2B;IgG Fc receptor II-b;CDw32;Fc-gamma RII-b;Fc-gamma-RIIb;FcRII-b;CD32;FCG2; IGFR2;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2b, κ
Isotype Control:Genie Fluor 488 Mouse IgG2b, κ Isotype Control[MPC-11]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P31994
Gene ID:2212
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform).

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