The Human CD31 Monoclonal Antibody (APC Conjugated, 158-2B3) offered by AssayGenie (Product Code: AGEL0942) is a cutting-edge tool for researchers studying CD31, a key cell surface protein involved in various physiological processes. This monoclonal antibody, specifically designed for use in flow cytometry applications, provides high specificity and sensitivity in detecting CD31 expression in human samples.CD31, also known as platelet endothelial cell adhesion molecule (PECAM-1), plays a crucial role in various cellular functions, including adhesion, migration, and signal transduction. Its presence on endothelial cells, platelets, and leukocytes underscores its significance in vascular biology and immune response regulation. The CD31 Monoclonal Antibody (APC Conjugated) enables researchers to investigate the expression levels and distribution of CD31 in different cell types, facilitating studies in immunology, angiogenesis, and cardiovascular research.
The incorporation of allophycocyanin (APC) as the conjugate in this monoclonal antibody provides enhanced signal amplification, allowing for improved detection and quantification of CD31-expressing cells in flow cytometry experiments. With its reliable performance and specificity for human CD31, this antibody is an invaluable tool for researchers seeking to elucidate the role of CD31 in health and disease, making it particularly advantageous for investigations related to vascular disorders, inflammation, and cancer biology.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P16284
Gene ID:
5175
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD31 is a 130-140 kD type I transmembrane glycoprotein also known as platelet endothelial cell adhesion molecule-1 (PECAM-1) or Endocam. It is expressed on monocytes, platelets, granulocytes, endothelial cells and lymphocyte subsets. CD31 has been reported to bind CD38 and be involved in wound healing, angiogenesis, and cellular migration in an inflammatory situation.