The FITC-conjugated Human CD303 Monoclonal Antibody (201A-AGEL1816) offered by AssayGenie is a cutting-edge tool for researchers studying CD303, a pivotal cell surface marker linked to immune regulation. This monoclonal antibody, engineered for high reactivity with human samples, is meticulously validated for use in diverse applications, notably in flow cytometry and immunofluorescence analyses. By specifically binding to the CD303 protein, this antibody enables precise detection and characterization of CD303 in a variety of cell types, offering invaluable insights for studies in immunology, virology, and infectious diseases.
CD303, also known as plasmacytoid dendritic cell antigen-1 (BDCA-2), is a key player in immune responses, particularly in viral infections and autoimmune conditions. As an essential marker for plasmacytoid dendritic cells, CD303 serves as a critical target for research into antiviral immune responses, vaccine development, and autoimmune disease mechanisms. By elucidating the role of CD303 in immune system modulation, researchers can gain crucial knowledge to develop innovative therapeutic strategies for combatting infectious diseases and autoimmune disorders.
Product Title:
FITC Anti-Human CD303 Antibody [201A]
SKU:
AGEL1816
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
201A
Synonyms:
BDCA2;CLECSF11;CLECSF7;DLEC;HECL;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG2a, κ
Isotype Control:
FITC Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:
Liquid
Conjugation:
FITC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
Q8WTT0
Gene ID:
170482
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD303, also known as BDCA-2 and CLEC4C, is a 38 kD type II transmembrane glycoprotein. It is a member of the C-type lectin superfamily. CD303 is expressed by plasmacytoid dendritic cells (pDCs) and is involved in cell adhesion, signaling, and antigen capture and processing. Crosslinking of CD303 inhibits the production of IFN-α/β and TLR-9 induced pDCs maturation.