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APC Anti-Human CD303 Antibody [201A] (AGEL1818)

SKU:
AGEL1818
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
€219 - €729
Frequently bought together:

Description

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APC Anti-Human CD303 Antibody [201A]

The Human CD303 Monoclonal Antibody (APC-Conjugated) is a vital tool for research into CD303, a cell surface marker associated with immune function and dendritic cell activity. This antibody, specifically designed for use in flow cytometry applications, is derived from a mouse hybridoma and offers high specificity and sensitivity in detecting CD303 in human samples.CD303, also known as blood dendritic cell antigen 2 (BDCA-2), is a key player in the immune response, particularly in antigen presentation and immune regulation. Its expression on plasmacytoid dendritic cells and its role in recognizing viral nucleic acids make it a crucial target for studies in virology, immunology, and vaccine development.

Researchers can utilize the Human CD303 Monoclonal Antibody (APC-Conjugated) to explore the function and distribution of CD303 in different cell populations, aiding in the investigation of immune responses to viral infections, autoimmune diseases, and cancer. By understanding the role of CD303, new therapeutic approaches and diagnostic tools may be developed to manipulate immune responses effectively.

Product Title:APC Anti-Human CD303 Antibody [201A]
SKU:AGEL1818
Size:20 Tests, 100 Tests, 200 Tests
Clone No:201A
Synonyms:BDCA2;CLECSF11;CLECSF7;DLEC;HECL;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:APC Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q8WTT0
Gene ID:170482
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD303, also known as BDCA-2 and CLEC4C, is a 38 kD type II transmembrane glycoprotein. It is a member of the C-type lectin superfamily. CD303 is expressed by plasmacytoid dendritic cells (pDCs) and is involved in cell adhesion, signaling, and antigen capture and processing. Crosslinking of CD303 inhibits the production of IFN-α/β and TLR-9 induced pDCs maturation.

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