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APC Anti-Human CD3 Antibody [OKT-3] (AGEL0059)

SKU:
AGEL0059
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2a
Clone:
OKT3
Conjugation:
APC
Applications:
FC
€89 - €299
Frequently bought together:

Description

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APC Anti-Human CD3 Antibody [OKT-3]

The Human CD3 Monoclonal Antibody (APC Conjugated) OKT3 (AGEL0059) is a vital tool for research involving CD3, a cell surface protein essential for T cell function. This monoclonal antibody, developed for use in flow cytometry applications, specifically targets the CD3 antigen, allowing for precise detection and characterization of T cells in human samples.CD3 is a crucial component of the T cell receptor complex, essential for T cell signaling and activation. Dysregulation of CD3 expression or function has been implicated in various immune disorders, including autoimmune diseases and immunodeficiencies. The APC conjugation of this antibody enables multi-color flow cytometry analysis, providing researchers with a powerful tool for studying T cell populations in different experimental settings.

The specificity and sensitivity of the Human CD3 Monoclonal Antibody (APC Conjugated) OKT3 (AGEL0059) make it an ideal choice for immunology and cell biology research. By targeting CD3, researchers can gain valuable insights into T cell development, activation, and function, ultimately advancing our understanding of immune responses and paving the way for innovative therapeutic strategies in the treatment of immune-related diseases.

Product Title:APC Anti-Human CD3 Antibody [OKT-3]
SKU:AGEL0059
Size:20 Tests, 100 Tests, 200 Tests
Clone No:OKT-3
Synonyms:T-cell surface glycoprotein CD3 epsilon chain;CD3E;T-cell surface antigen T3/Leu-4 epsilon chain;CD3e;CD3E;T3E;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:APC Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P07766
Gene ID:916
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD3ε is a 20 kD chain of the CD3/T cell receptor (TCR) complex, which is composed of two CD3ε, one CD3γ, one CD3δ, one CD3ζ (CD247), and a T cell receptor (α/β or γ/δ) heterodimer. It is found on all mature T lymphocytes, NK T cells, and some thymocytes. CD3, also known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen recognition, signal transduction, and T cell activation.

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