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GenieFluor 488 Anti-Human CD3 Antibody [OKT-3] (AGEL0062)

SKU:
AGEL0062
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2a
Clone:
OKT3
Conjugation:
AF 488
Applications:
FC
$167 - $563
Frequently bought together:

Description

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GenieFluor 488 Anti-Human CD3 Antibody [OKT-3]

The Human CD3 Monoclonal Antibody (Alexa Fluor 488 Conjugated) OKT3 (AGEL0062) is a potent tool for researchers studying immune responses and T-cell activation. This antibody, conjugated with Alexa Fluor 488 for fluorescent detection, specifically targets the CD3 protein found on the surface of T-cells. By binding to CD3, the antibody enables precise visualization and analysis of T-cell populations in various research applications, including flow cytometry and immunofluorescence.CD3 is a crucial component of the T-cell receptor complex, essential for T-cell activation and function in the immune response. The OKT3 monoclonal antibody recognizes the CD3 antigen with high specificity and sensitivity, allowing for detailed investigation of T-cell behavior and interactions in immunology research.

Its compatibility with fluorescence-based techniques enhances the accuracy and efficiency of experiments focusing on T-cell signaling pathways, antigen recognition, and immune cell profiling.Researchers interested in studying T-cell biology, immune responses, and immune-related disorders will find the Human CD3 Monoclonal Antibody (Alexa Fluor 488 Conjugated) OKT3 (AGEL0062) to be a valuable resource for their investigations. With its reliable performance and ability to facilitate detailed T-cell analysis, this antibody is a vital asset in unraveling the complexities of the immune system and advancing our understanding of T-cell-mediated immunity.

Product Title:GenieFluor 488 Anti-Human CD3 Antibody [OKT-3]
SKU:AGEL0062
Size:20 Tests, 100 Tests, 200 Tests
Clone No:OKT-3
Synonyms:T-cell surface glycoprotein CD3 epsilon chain;CD3E;T-cell surface antigen T3/Leu-4 epsilon chain;CD3e;CD3E;T3E;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:Genie Fluor 488 Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P07766
Gene ID:916
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD3ε is a 20 kD chain of the CD3/T cell receptor (TCR) complex, which is composed of two CD3ε, one CD3γ, one CD3δ, one CD3ζ (CD247), and a T cell receptor (α/β or γ/δ) heterodimer. It is found on all mature T lymphocytes, NK T cells, and some thymocytes. CD3, also known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen recognition, signal transduction, and T cell activation.

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