The Human CD3 Monoclonal Antibody (AF647 Conjugated, OKT3) from Assay Genie (AGEL0606) is a cutting-edge tool designed for precise research applications focusing on CD3, an essential component of the T-cell receptor complex. This advanced antibody, conjugated with AF647 for enhanced visualization, is specifically tailored for human samples and is extensively validated for various analytical techniques.CD3 is a quintessential marker for T-cells, playing a pivotal role in orchestrating immune responses and maintaining immune system balance. This monoclonal antibody, developed with the OKT3 clone, provides exceptional specificity and sensitivity for detecting and studying CD3 expression in diverse cell populations.
Its utilization is particularly advantageous in immunology research, immunophenotyping studies, and investigations into T-cell-mediated diseases.By leveraging the capabilities of the Human CD3 Monoclonal Antibody (AF647 Conjugated, OKT3), researchers can gain deeper insights into T-cell biology, immune system function, and the molecular mechanisms underlying immune-related disorders. Explore the intricate world of T-cell biology with confidence and precision using this state-of-the-art reagent from Assay Genie.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P07766
Gene ID:
916
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD3ε is a 20 kD chain of the CD3/T cell receptor (TCR) complex, which is composed of two CD3ε, one CD3γ, one CD3δ, one CD3ζ (CD247), and a T cell receptor (α/β or γ/δ) heterodimer. It is found on all mature T lymphocytes, NK T cells, and some thymocytes. CD3, also known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen recognition, signal transduction, and T cell activation.