The Human CD29 Monoclonal Antibody (PE/Cyanine7 Conjugated) (TS2/16 (2/1)) is a cutting-edge tool for researchers studying cell adhesion and signal transduction pathways. This antibody, offered by AssayGenie, is specifically designed for detecting the CD29 protein, also known as integrin beta-1, which plays a crucial role in cell-matrix adhesion and cell signaling.CD29 is a key player in various cellular processes such as cell migration, proliferation, and differentiation. The PE/Cyanine7 conjugation of this monoclonal antibody enables efficient fluorescence-based detection and analysis, making it ideal for flow cytometry applications and immunofluorescence studies.With its high specificity and sensitivity to human samples, this antibody is a valuable tool for research in diverse fields such as cell biology, immunology, and cancer biology.
By targeting CD29, researchers can gain insights into the mechanisms underlying cell adhesion and its implications in disease processes, potentially leading to the development of novel therapeutic strategies.Overall, the Human CD29 Monoclonal Antibody (PE/Cyanine7 Conjugated) (TS2/16 (2/1)) from AssayGenie is a reliable reagent for investigating the function and regulation of CD29 in cellular interactions, providing a foundation for advancing our understanding of cell biology and disease mechanisms.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P05556
Gene ID:
3688
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD29 is a 130 kD single chain type I glycoprotein also known as integrin β1, VLA-β chain, or gpIIa. It is broadly expressed on a majority of hematopoietic and non-hematopoietic cells, including leukocytes (although at low level on granulocytes), platelets, fibroblasts, endothelial cells, epithelial cells, and mast cells. CD29 is a member of the integrin family. It is non-covalently associated with integrin α1-α6 chains to form VLA-1 to VLA-6 molecules, respectively. Integrins, which include CD29, bind to several cell surface (e.g. VCAM-1, MadCAM-1) and extracellular matrix molecules. CD29 acts as a fibronectin receptor and is involved in a variety of cell-cell and cell-matrix interactions.