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PE/Cyanine5 Anti-Human CD29 Antibody [TS2/16.2.1] (AGEL0936)

SKU:
AGEL0936
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
€219 - €769
Frequently bought together:

Description

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PE/Cyanine5 Anti-Human CD29 Antibody [TS2/16.2.1]

The Human CD29 Monoclonal Antibody PE/Cyanine5 Conjugated (TS2/16) is a cutting-edge tool designed for research purposes involving the CD29 protein, also known as Integrin beta 1. This monoclonal antibody, conjugated with PE/Cyanine5, offers high specificity and sensitivity for detecting CD29 expression in human samples. Validated for use in flow cytometry applications, it enables precise identification and quantification of CD29 on the surface of various cell types.CD29 is a crucial cell surface protein that plays a pivotal role in cell adhesion and signaling processes.

Its involvement in cell-to-cell and cell-to-extracellular matrix interactions makes it a key player in physiological and pathological events like tissue development, wound healing, and cancer metastasis. By targeting CD29 with this monoclonal antibody, researchers can gain insights into its function and regulation in different biological contexts, paving the way for advancements in fields such as cell biology, immunology, and cancer research.

Product Title:PE/Cyanine5 Anti-Human CD29 Antibody [TS2/16.2.1]
SKU:AGEL0936
Size:20 Tests, 100 Tests, 200 Tests
Clone No:TS2/16.2.1
Synonyms:Integrin beta-1;ITB1;Itgb1;Fibronectin receptor subunit beta;VLA-4 subunit beta;CD29;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P05556
Gene ID:3688
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD29 is a 130 kD single chain type I glycoprotein also known as integrin β1, VLA-β chain, or gpIIa. It is broadly expressed on a majority of hematopoietic and non-hematopoietic cells, including leukocytes (although at low level on granulocytes), platelets, fibroblasts, endothelial cells, epithelial cells, and mast cells. CD29 is a member of the integrin family. It is non-covalently associated with integrin α1-α6 chains to form VLA-1 to VLA-6 molecules, respectively. Integrins, which include CD29, bind to several cell surface (e.g. VCAM-1, MadCAM-1) and extracellular matrix molecules. CD29 acts as a fibronectin receptor and is involved in a variety of cell-cell and cell-matrix interactions.

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