The Human CD29 Monoclonal Antibody (PE-conjugated) TS2/16 (2-1) (AGEL0215) is a valuable tool for researchers studying CD29, a key cell surface protein involved in cell adhesion and migration processes. This monoclonal antibody, conjugated with PE for enhanced detection, is specifically designed for use in flow cytometry applications and is highly reactive with human samples.CD29, also known as integrin beta-1, plays a crucial role in cell-cell and cell-matrix interactions, influencing various cellular functions such as proliferation, differentiation, and survival. By targeting CD29 with this precision monoclonal antibody, researchers can accurately analyze and quantify CD29 expression levels in different cell populations, providing insights into processes related to tissue development, wound healing, and immune response regulation.
With its specificity for CD29 and compatibility with flow cytometry techniques, the Human CD29 Monoclonal Antibody (PE-conjugated) TS2/16 (2-1) (AGEL0215) is an essential tool for investigations in cell biology, immunology, and cancer research. Unlock the potential of CD29 research with this high-quality antibody for precise and reliable detection of CD29 expression in human samples.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P05556
Gene ID:
3688
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD29 is a 130 kD single chain type I glycoprotein also known as integrin β1, VLA-β chain, or gpIIa. It is broadly expressed on a majority of hematopoietic and non-hematopoietic cells, including leukocytes (although at low level on granulocytes), platelets, fibroblasts, endothelial cells, epithelial cells, and mast cells. CD29 is a member of the integrin family. It is non-covalently associated with integrin α1-α6 chains to form VLA-1 to VLA-6 molecules, respectively. Integrins, which include CD29, bind to several cell surface (e.g. VCAM-1, MadCAM-1) and extracellular matrix molecules. CD29 acts as a fibronectin receptor and is involved in a variety of cell-cell and cell-matrix interactions.