The Human CD29 Monoclonal Antibody (Alexa Fluor 488 Conjugated) TS2/16 (AGEL0217) from Assay Genie is a cutting-edge tool designed for researchers studying CD29, a key cell surface protein involved in cell adhesion and migration. This monoclonal antibody, conjugated with the highly fluorescent Alexa Fluor 488, offers exceptional specificity and sensitivity in detecting CD29 in human samples.CD29, also known as integrin beta-1, plays a crucial role in cell-cell and cell-matrix interactions, making it a central player in processes like cell signaling, differentiation, and tissue morphogenesis. Its functions extend to various biological processes, including immune response modulation, wound healing, and cancer progression. As such, the Human CD29 Monoclonal Antibody is an invaluable tool for investigating the role of CD29 in diverse research areas such as immunology, developmental biology, and oncology.
The TS2/16 monoclonal antibody specifically targets CD29, enabling precise and reliable detection and quantification of this protein in different cell types and experimental settings. Its Alexa Fluor 488 conjugation further enhances its utility by providing bright, stable fluorescence for imaging and flow cytometry applications. Researchers can leverage this antibody to gain insights into the complex mechanisms involving CD29 and its impact on cellular behavior, offering new avenues for therapeutic development and disease understanding.Overall, the Human CD29 Monoclonal Antibody (Alexa Fluor 488 Conjugated) TS2/16 (AGEL0217) is a superior reagent that empowers researchers to delve deeper into the functional roles of CD29, paving the way for breakthrough discoveries in biomedical research and clinical applications.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P05556
Gene ID:
3688
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD29 is a 130 kD single chain type I glycoprotein also known as integrin β1, VLA-β chain, or gpIIa. It is broadly expressed on a majority of hematopoietic and non-hematopoietic cells, including leukocytes (although at low level on granulocytes), platelets, fibroblasts, endothelial cells, epithelial cells, and mast cells. CD29 is a member of the integrin family. It is non-covalently associated with integrin α1-α6 chains to form VLA-1 to VLA-6 molecules, respectively. Integrins, which include CD29, bind to several cell surface (e.g. VCAM-1, MadCAM-1) and extracellular matrix molecules. CD29 acts as a fibronectin receptor and is involved in a variety of cell-cell and cell-matrix interactions.