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GenieFluor 647 Anti-Human CD27 Antibody [O323] (AGEL1715)

SKU:
AGEL1715
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2a,k
Clone:
O323
Conjugation:
AF 647
€139 - €469
Frequently bought together:

Description

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GenieFluor 647 Anti-Human CD27 Antibody [O323]

The Human CD27 Monoclonal Antibody (AF647 Conjugated) is a cutting-edge tool for researchers investigating CD27, a cell surface protein involved in immune cell activation and differentiation. This monoclonal antibody, labeled with AF647 for fluorescence detection, offers high specificity and sensitivity in detecting CD27 in human samples across various experimental techniques.CD27, a member of the tumor necrosis factor receptor superfamily, plays a vital role in immune responses by providing co-stimulatory signals for T cell activation and promoting B cell differentiation. Its involvement in regulating immune cell functions makes it a key target for studies in immunology, vaccine development, and cancer immunotherapy.

The conjugated AF647 allows for easy visualization and quantification of CD27 expression, facilitating detailed analysis of immune cell subsets and functional responses.By utilizing the Human CD27 Monoclonal Antibody (AF647 Conjugated), researchers can delve deeper into the mechanisms underlying immune activation and modulation, paving the way for innovative discoveries in immunotherapy, infectious diseases, and autoimmune conditions. This versatile antibody provides a valuable tool for elucidating the complex interplay of CD27 in immune regulation and holds promise for advancing our understanding of immunological processes in health and disease.

Product Title:GenieFluor 647 Anti-Human CD27 Antibody [O323]
SKU:AGEL1715
Size:20 Tests, 100 Tests, 200 Tests
Clone No:O323
Synonyms:CD27L receptor;T-cell activation antigen CD27;T14;S152;TNFRSF7;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Genie Fluor 647 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P26842
Gene ID:939
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD27 is a 50-55 kD type I membrane protein also known as S152 and T14. It is a lymphocyte-specific member of the TNF-receptor superfamily. CD27 is expressed on medullary thymocytes, virtually all mature T cells, some B cells, and NK cells. CD27 binds to CD70 and plays an important role in costimulation of T cell activation, and regulation of B cell differentiation and proliferation. The cytoplasmic domains of CD27 have also been shown to interact with TRAF2 and TRAF5 to elicit NF-κB and SAPK/JNK activation.

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