The Human CD235 Monoclonal Antibody (PE/Cyanine5 Conjugated) (HIR2) is a cutting-edge tool designed for researchers delving into the intricacies of CD235, a cell surface marker known for its roles in blood cell differentiation and blood group typing. This antibody, meticulously developed for specificity and sensitivity, is optimized for flow cytometry applications, providing precise identification and characterization of CD235-expressing cells with exceptional fluorescence detection.CD235, also referred to as glycophorin A, plays a key role in erythropoiesis and red blood cell function, making it a crucial target for studies in hematology, transfusion medicine, and blood-related disorders.
Its unique expression patterns and functions offer valuable insights into blood cell development and differentiation, with implications for diseases such as anemia, hemolytic disorders, and blood transfusion compatibility. Deepening our understanding of CD235 through accurate detection and analysis can pave the way for advancements in personalized medicine and transfusion therapy.Explore the dynamic world of blood cell biology with the Human CD235 Monoclonal Antibody (PE/Cyanine5 Conjugated) (HIR2) and unravel the mysteries of CD235 expression and function in various physiological and pathological contexts.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P02724 P06028
Gene ID:
2993
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
The HIR2 antibody reacts with a common epitope of glycophorin A (CD235a) and glycophorin B (CD235b). Glycophorin A is the major sialoglycoprotein expressed on red blood cell membrane, and erythroid precursors. Glycophorin A shares strong homology with glycophorin B. The HIR2 antibody recognizes human RBCs and erythroid precursors and is useful in erythroid cell development studies. Mature, non-nucleated red blood cells are characteristically glycophorin A positive, but CD45 and CD71 negative.