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Biotin Anti-Human CD235 Antibody [HIR2] (AGEL0303)

SKU:
AGEL0303
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2b
Clone:
HIR2
Conjugation:
Biotin
Applications:
FC
€159 - €329
Frequently bought together:

Description

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Biotin Anti-Human CD235 Antibody [HIR2]

The Human CD235 Monoclonal Antibody (Biotin Conjugated) is a vital tool for researchers studying CD235, a cell surface glycoprotein involved in red blood cell development and function. This monoclonal antibody, conjugated with biotin for enhanced detection capabilities, is specifically designed for use with human samples and has been rigorously validated for various applications including flow cytometry and immunohistochemistry.CD235, also known as glycophorin A, is a crucial component of red blood cells, playing a key role in their structure and function. Research involving CD235 is particularly relevant in the fields of hematology, transfusion medicine, and blood disorders.

By specifically targeting and binding to CD235, this monoclonal antibody enables precise detection and analysis of red blood cells in research settings, facilitating a deeper understanding of their biology and function.Furthermore, the utilization of the Human CD235 Monoclonal Antibody (Biotin Conjugated) is essential for investigations into conditions affecting red blood cells, such as anemias, hemoglobin disorders, and hematological malignancies. By gaining insights into the role of CD235 in these diseases, researchers can potentially uncover novel therapeutic targets and diagnostic markers, ultimately advancing the field of hematology and improving patient care.

Product Title:Biotin Anti-Human CD235 Antibody [HIR2]
SKU:AGEL0303
Size:25µg, 100µg
Clone No:HIR2
Synonyms:Glycophorin-A/B;GYPA/B;MN sialoglycoprotein;SS-active sialoglycoprotein;PAS-2/3;Sialoglycoprotein alpha/delta;CD235a/b;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2b, κ
Isotype Control:Biotin Mouse IgG2b, κ Isotype Control[MPC-11]
Form:Liquid
Conjugation:Biotin
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P02724 P06028
Gene ID:2993
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:The HIR2 antibody reacts with a common epitope of glycophorin A (CD235a) and glycophorin B (CD235b). Glycophorin A is the major sialoglycoprotein expressed on red blood cell membrane, and erythroid precursors. Glycophorin A shares strong homology with glycophorin B. The HIR2 antibody recognizes human RBCs and erythroid precursors and is useful in erythroid cell development studies. Mature, non-nucleated red blood cells are characteristically glycophorin A positive, but CD45 and CD71 negative.

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