The CD21 Monoclonal Antibody (BU32) is a biotin-conjugated antibody designed for the detection and analysis of the CD21 protein in human samples. CD21, also known as complement receptor 2 (CR2), plays a crucial role in the immune system by enhancing B cell activation and facilitating antigen presentation.This monoclonal antibody, produced using advanced technology, offers high specificity and sensitivity for CD21 detection in various cell types. Its biotin conjugation provides a convenient method for signal amplification in experiments such as immunohistochemistry and flow cytometry.By targeting the CD21 protein, researchers can gain insights into the regulation of immune responses, particularly in the context of B cell function and antibody production.
This antibody is a valuable tool for studies in immunology, infectious diseases, and autoimmune disorders, as well as for exploring the role of CD21 in vaccine development and immune system modulation.Overall, the CD21 Monoclonal Antibody (BU32) is a reliable reagent for investigating the molecular mechanisms underlying immune responses and B cell activity, making it an essential component in research related to immunology and infectious diseases.
Product Title:
Biotin Anti-Human CD21 Antibody [BU32]
SKU:
AGEL0202
Size:
25µg, 100µg
Clone No:
BU32
Synonyms:
Complement receptor type 2;CR2;Cr2;Complement C3d receptor;Epstein-Barr virus receptor;EBV receptor;CD21;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG1, κ
Isotype Control:
Biotin Mouse IgG1, κ Isotype Control[MOPC-21]
Form:
Liquid
Conjugation:
Biotin
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:
P20023
Gene ID:
1380
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD21 is a 145 kD transmembrane protein also known as complement C3d receptor (C3dR), complement receptor 2 (CR2), and Epstein-Barr virus receptor. CD21 is expressed on B cells, follicular dendritic cells, subsets of normal thymocytes and T cells, and some epithelial cells. CD21 is the receptor used by Epstein-Barr virus to infect B cells and is also the complement receptor for C3d. CD21 has also been shown to interact with a number of proteins, including CD23, CD19, annexin VI, CD81, iC3b, complement receptor 1 (CR1, CD35), and interferon-alpha 1 (IFN-α1).