The Human CD200 Monoclonal Antibody (APC-conjugated, clone OX-104, Cat# AGEL1812) from Assay Genie is a powerful tool for research focused on CD200, a cell surface glycoprotein with immunosuppressive properties. This monoclonal antibody is specifically designed for use in flow cytometry applications, enabling precise detection and analysis of CD200 expression on various cell types. CD200, also known as OX2, is a key regulatory molecule involved in immune tolerance and the prevention of excessive immune responses. Its interaction with its receptor plays a crucial role in maintaining immune homeostasis and preventing autoimmunity.
Research into CD200 has broad implications in immunology, neurobiology, and cancer immunotherapy, making this APC-conjugated monoclonal antibody an invaluable tool for scientists studying these areas.By utilizing the Human CD200 Monoclonal Antibody (APC-conjugated) in your experiments, you can gain insights into the role of CD200 in immune regulation and its potential as a therapeutic target in various diseases. Trust Assay Genie's high-quality antibody products to support your research and help advance our understanding of CD200 biology.
Product Title:
APC Anti-Human CD200 Antibody [OX-104]
SKU:
AGEL1812
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
OX-104
Synonyms:
MOX1;MOX2;My033;CD 200;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG1, κ
Isotype Control:
APC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:
Liquid
Conjugation:
APC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P41217
Gene ID:
4345
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD200, also known as OX2, is a member of the immunoglobulin superfamily (IgSF). It is a monomorphic cell surface glycoprotein that is expressed on thymocytes, neurons, endothelium, follicular dendritic cells in all lymphoid organs, a subset of CD34+ progenitor cells, and at low levels on some smooth muscle and B lymphocytes. It is not expressed on NK cells, monocytes, granulocytes, or platelets. CD200 costimulates T cell proliferation. It may regulate myeloid cell activity in a variety of tissues. The interaction between CD200 (OX2) and CD200 receptor (OX2R) system is of importance in the control of macrophage and granulocyte activation, which may contribute to pathways that suppress and limit macrophage induced inflammatory damage in tissue.