The Human CD2 Monoclonal Antibody PE-conjugated (TS1/8) is a versatile tool for researchers studying immune cell interactions and cell signaling pathways. This antibody, conjugated with phycoerythrin (PE) for flow cytometry applications, specifically targets the CD2 protein found on the surface of T cells and natural killer cells.CD2 is a crucial cell adhesion molecule involved in immune responses and T cell activation. By using this monoclonal antibody, researchers can accurately detect and analyze CD2 expression levels on various cell types, providing valuable insights into immune system function and potential therapeutic targets.With its high specificity and sensitivity, the TS1/8 antibody is suitable for a wide range of experiments, including immunophenotyping, cell sorting, and studying cell-cell interactions.
Its validated performance in flow cytometry ensures reliable and reproducible results, making it an essential tool for immunologists, cancer researchers, and anyone exploring the complexities of the human immune system.By utilizing the Human CD2 Monoclonal Antibody PE-conjugated (TS1/8), researchers can advance their understanding of immune responses, immune cell activation, and the development of targeted therapies for various immune-related disorders.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P06729
Gene ID:
914
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD2 is a 50 kD type I transmembrane glycoprotein also known as LFA-2, T11, and sheep red blood cell receptor (SRBC-R). This immunoglobulin superfamily member is expressed on thymocytes, T lymphocytes, NK cells, and thymic B cell subsets. The major ligand for CD2 is CD58 (also known as LFA-3). CD2 has also been reported to bind CD48, CD59, and CD15. CD2 plays a critical role in alternative T cell activation, T cell signaling, and cell-cell adhesion.