The Human CD1a Monoclonal Antibody (Biotin Conjugated, OKT-6, AGEL1586) from Assay Genie is a specialized tool for research targeting CD1a, a cell surface molecule crucial for antigen presentation and immune responses. This monoclonal antibody is uniquely engineered for high specificity and sensitivity in detecting human CD1a, making it a valuable asset in immunology and cancer research.CD1a is a key player in the immune system, participating in the activation of T cells and the recognition of lipid antigens. By targeting CD1a with this monoclonal antibody, researchers can study its expression and function in various cell types, uncovering insights into immune processes and potential therapeutic targets.
The biotin conjugation of this antibody further expands its utility, facilitating easy detection and analysis in diverse experimental setups.With its reliability, specificity, and versatility, the Human CD1a Monoclonal Antibody (Biotin Conjugated, OKT-6, AGEL1586) empowers researchers to delve deeper into the complexities of immune responses and potentially discover novel strategies for combating diseases such as cancer and autoimmune disorders. Explore the intricate world of immune regulation with this cutting-edge antibody from Assay Genie.
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:
P06126
Gene ID:
909
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD1a is a 49 kD member of the immunoglobulin superfamily also known as T6 and R4. It is a type I membrane glycoprotein with structural similarities to MHC class I and is non-covalently associated with β2-microglobulin. CD1a plays a role in non-peptide glycolipid antigen presentation to CD1-restricted T cells. It is expressed on cortical double positive and single positive thymocytes, Langerhans cells, and dendritic cells. In addition to antigen presentation, CD1a has been implicated in thymic T cell development.