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PE Anti-Human CD184/CXCR4 Antibody [12G5] (AGEL1797)

SKU:
AGEL1797
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
€219 - €709
Frequently bought together:

Description

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PE Anti-Human CD184/CXCR4 Antibody [12G5]

The Human CD184 (CXCR4) Monoclonal Antibody (PE Conjugated) (12G5) is a powerful tool for researchers studying CXCR4, a key chemokine receptor involved in cell migration and signaling. This monoclonal antibody, conjugated with PE for enhanced detection in flow cytometry applications, specifically targets the human CD184 protein.CXCR4, also known as stromal cell-derived factor 1 receptor, plays a crucial role in diverse biological processes such as immune response, hematopoiesis, and cancer metastasis. By targeting CXCR4, researchers can gain insights into how this receptor contributes to various physiological and pathological processes.The PE-conjugated 12G5 antibody offers high sensitivity and specificity in detecting CD184 expression, allowing for precise analysis of CXCR4 in different cell populations.

Its validation for use in flow cytometry makes it a valuable tool for immunology studies, cancer research, and investigations into inflammatory diseases.Understanding the role of CXCR4 in cell signaling and migration is essential for unraveling its involvement in diseases like cancer, HIV infection, and inflammatory conditions. The Human CD184 (CXCR4) Monoclonal Antibody (PE Conjugated) (12G5) from Assay Genie provides researchers with a reliable reagent to advance their studies and uncover new insights into the functions of CXCR4 in health and disease.

Product Title:PE Anti-Human CD184/CXCR4 Antibody [12G5]
SKU:AGEL1797
Size:20 Tests, 100 Tests, 200 Tests
Clone No:12G5
Synonyms:FB22;Fusin;HM89;LCR1;LAP-3;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:PE Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P61073
Gene ID:7852
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD184, also known as fusin or CXCR4, is a 45 kD seven transmembrane G-protein-linked CXC chemokine receptor. CD184 is widely expressed on blood and tissue cells, including B and T cells, monocytes, macrophages, dendritic cells, granulocytes, megakaryocytes/platelets, lymphoid, myeloid precursor cells, endothelial cells, epithelial cells, astrocytes, and neurons, among other tissue cells. CD184 is the receptor for CXC chemokine SDF-1, mediates blood cell migration, and is involved in B lymphopoiesis and myelopoiesis, cardiogenesis, blood vessel formation, and cerebellar development. CXCR4 is also a coreceptor of X4 HIV-1 and an alternative receptor for some isolates of HIV-2.

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