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APC Anti-Human CD184/CXCR4 Antibody [12G5] (AGEL1798)

SKU:
AGEL1798
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
€249 - €829
Frequently bought together:

Description

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APC Anti-Human CD184/CXCR4 Antibody [12G5]

The Human CD184 (CXCR4) Monoclonal Antibody (APC Conjugated, 12G5) is a cutting-edge tool for researchers exploring the role of CXCR4, a key chemokine receptor involved in various physiological processes, including immune cell migration and cancer metastasis. This antibody, developed by Assay Genie, is specifically tailored for use in flow cytometry applications, offering high specificity and sensitivity for detecting CXCR4 expression in human samples.CXCR4, a G protein-coupled receptor, is known for its crucial involvement in regulating immune cell trafficking and homing to specific tissues, as well as its implications in cancer progression and metastasis.

The expression and activity of CXCR4 have been linked to various pathological conditions, making it a significant target for research in immunology, oncology, and infectious diseases. By utilizing the Human CD184 Monoclonal Antibody, researchers can gain valuable insights into the function and regulation of CXCR4 in different cell types, paving the way for innovative studies and potential therapeutic interventions.

Product Title:APC Anti-Human CD184/CXCR4 Antibody [12G5]
SKU:AGEL1798
Size:20 Tests, 100 Tests, 200 Tests
Clone No:12G5
Synonyms:FB22;Fusin;HM89;LCR1;LAP-3;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:APC Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P61073
Gene ID:7852
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD184, also known as fusin or CXCR4, is a 45 kD seven transmembrane G-protein-linked CXC chemokine receptor. CD184 is widely expressed on blood and tissue cells, including B and T cells, monocytes, macrophages, dendritic cells, granulocytes, megakaryocytes/platelets, lymphoid, myeloid precursor cells, endothelial cells, epithelial cells, astrocytes, and neurons, among other tissue cells. CD184 is the receptor for CXC chemokine SDF-1, mediates blood cell migration, and is involved in B lymphopoiesis and myelopoiesis, cardiogenesis, blood vessel formation, and cerebellar development. CXCR4 is also a coreceptor of X4 HIV-1 and an alternative receptor for some isolates of HIV-2.

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