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PE Anti-Human CD183/CXCR3 Antibody [G025H7] (AGEL1795)

SKU:
AGEL1795
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
€239 - €729
Frequently bought together:

Description

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PE Anti-Human CD183/CXCR3 Antibody [G025H7]

The Human CD183 (CXCR3) Monoclonal Antibody PE-conjugated (G025H7) is a powerful tool for researchers studying CXCR3, a chemokine receptor involved in immune responses and inflammation. This monoclonal antibody, validated for use in flow cytometry applications, specifically targets and detects the CXCR3 protein in human samples with high sensitivity and specificity.CXCR3 is a key player in the immune system, regulating the recruitment and activation of immune cells in response to inflammatory signals. Its role in directing immune cell migration to sites of infection or inflammation makes it a vital target for research in fields such as immunology, infectious diseases, and autoimmune disorders.

By using this PE-conjugated monoclonal antibody, researchers can effectively analyze CXCR3 expression on various cell populations, aiding in the understanding of immune responses and inflammatory processes.With its precise targeting of CXCR3, this monoclonal antibody opens up opportunities for in-depth investigations into the mechanisms underlying immune cell trafficking and inflammation. It offers reliable results and enhanced clarity in flow cytometry analyses, enabling researchers to unravel the complexities of CXCR3-mediated immune responses and potentially identify new therapeutic targets for immune-related diseases.

Product Title:PE Anti-Human CD183/CXCR3 Antibody [G025H7]
SKU:AGEL1795
Size:20 Tests, 100 Tests, 200 Tests
Clone No:G025H7
Synonyms:CXCR3;GPR9;CXC-R3;CXCR-3;CKR-L2;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P49682
Gene ID:2833
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:Human CXCR3, also known as GPR9, is a chemokine receptor that binds CXCL9, CXCL10, and CXCL11. It is a 38 kD seven-pass transmembrane receptor coupled to G-protein. CXCR3 is highly expressed by T cells (Th1), natural killer cells (NK cells), dendritic cells, mast cells, alveolar macrophages, eosinophils, and human airway epithelial cells. CXCR3 is important for effector lymphocyte recruitment into inflamed tissue in various inflammatory and autoimmune diseases, such as chronically inflamed liver, Crohn's disease, rheumatoid arthritis, multiple sclerosis, and inflammatory skin diseases.

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