The Human CD183 (CXCR3) Monoclonal Antibody FITC Conjugated (G025H7) is a powerful tool for researchers studying the CD183 (CXCR3) cell surface molecule. This monoclonal antibody, conjugated with FITC for fluorescence detection, is specifically designed for use in flow cytometry and immunofluorescence applications.CXCR3 is a chemokine receptor known for its role in immune cell migration and activation, particularly in the context of inflammation and immune response modulation. By targeting CXCR3 with this antibody, researchers can effectively detect and analyze the expression of this critical molecule in various cell types, providing insights into its function in immune regulation and disease pathology.
With its high reactivity with human samples and validated performance in fluorescence-based assays, the Human CD183 (CXCR3) Monoclonal Antibody FITC Conjugated (G025H7) holds promise for advancing research in immunology, inflammation, and related fields. Whether investigating immune cell behavior in cancer, autoimmune diseases, or infectious conditions, this antibody offers a precise tool for studying the role of CXCR3 in immune modulation and disease progression.
Product Title:
FITC Anti-Human CD183/CXCR3 Antibody [G025H7]
SKU:
AGEL1794
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
G025H7
Synonyms:
CXCR3;GPR9;CXC-R3;CXCR-3;CKR-L2;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG1, κ
Isotype Control:
FITC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:
Liquid
Conjugation:
FITC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P49682
Gene ID:
2833
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
Human CXCR3, also known as GPR9, is a chemokine receptor that binds CXCL9, CXCL10, and CXCL11. It is a 38 kD seven-pass transmembrane receptor coupled to G-protein. CXCR3 is highly expressed by T cells (Th1), natural killer cells (NK cells), dendritic cells, mast cells, alveolar macrophages, eosinophils, and human airway epithelial cells. CXCR3 is important for effector lymphocyte recruitment into inflamed tissue in various inflammatory and autoimmune diseases, such as chronically inflamed liver, Crohn's disease, rheumatoid arthritis, multiple sclerosis, and inflammatory skin diseases.