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APC Anti-Human CD183/CXCR3 Antibody [G025H7] (AGEL1796)

SKU:
AGEL1796
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
$299 - $995
Frequently bought together:

Description

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APC Anti-Human CD183/CXCR3 Antibody [G025H7]

The Human CD183 (CXCR3) Monoclonal Antibody (APC-conjugated) (G025H7-AGEL1796) is a cutting-edge tool for researchers studying CXCR3, a chemokine receptor involved in immune responses and inflammation. This monoclonal antibody, designed for use with human samples, is highly specific and reliable in various applications, including flow cytometry and immunofluorescence.CXCR3, a receptor for the chemokines CXCL9, CXCL10, and CXCL11, is crucial for the recruitment of immune cells to sites of inflammation and plays a key role in regulating immune cell function.

By targeting CXCR3 with this monoclonal antibody, researchers can investigate its expression and activity in different cell types and disease contexts, such as autoimmune diseases, infectious diseases, and cancer.Additionally, understanding the role of CXCR3 in immune responses and inflammation is essential for developing targeted therapies that modulate immune cell trafficking and function. The Human CD183 (CXCR3) Monoclonal Antibody (APC-conjugated) provides a powerful tool for advancing research in immunology, inflammatory diseases, and therapeutics.

Product Title:APC Anti-Human CD183/CXCR3 Antibody [G025H7]
SKU:AGEL1796
Size:20 Tests, 100 Tests, 200 Tests
Clone No:G025H7
Synonyms:CXCR3;GPR9;CXC-R3;CXCR-3;CKR-L2;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:APC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P49682
Gene ID:2833
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:Human CXCR3, also known as GPR9, is a chemokine receptor that binds CXCL9, CXCL10, and CXCL11. It is a 38 kD seven-pass transmembrane receptor coupled to G-protein. CXCR3 is highly expressed by T cells (Th1), natural killer cells (NK cells), dendritic cells, mast cells, alveolar macrophages, eosinophils, and human airway epithelial cells. CXCR3 is important for effector lymphocyte recruitment into inflamed tissue in various inflammatory and autoimmune diseases, such as chronically inflamed liver, Crohn's disease, rheumatoid arthritis, multiple sclerosis, and inflammatory skin diseases.

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