The Human CD18 Monoclonal Antibody (PERCP-Cyanine5.5 Conjugated) (TS1/18) is a key tool for researchers studying CD18, a cell surface molecule with essential roles in immune function. This monoclonal antibody, conjugated with PERCP-Cyanine5.5, is specifically designed for use in flow cytometry applications targeting human samples.CD18 is a critical component of integrin receptors, playing a central role in cell adhesion and migration processes crucial for immune responses. The TS1/18 Monoclonal Antibody binds specifically to CD18, enabling precise detection and analysis of this important protein in various cell types.
Researchers in immunology, inflammation, and cell biology will find this antibody invaluable for investigating the role of CD18 in immune cell interactions and related pathways.By utilizing the TS1/18 Monoclonal Antibody, researchers can delve deeper into the mechanisms underlying immune cell function and inflammatory processes. This antibody is a valuable tool for studies exploring immune system regulation, inflammatory diseases, and therapeutic interventions targeting CD18-mediated pathways.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P05107
Gene ID:
3689
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD18 is a 90-95 kD type I transmembrane protein also known as integrin β2 subunit, LFA-1 β subunit, and β2 integrin. CD18 non-covalently associates with CD11a, CD11b or CD11c. CD18 is expressed on all leukocytes. CD18 and associated α chains function in adhesion and signaling in hematopoietic cells.