The Human CD18 Monoclonal Antibody (PE-Cyanine5.5 Conjugated) - TS1/18, 1-2-11 (AGEL0983) offered by AssayGenie is a specialized tool for research involving the CD18 protein, an important cell surface molecule involved in immune cell adhesion and activation. This monoclonal antibody, conjugated with PE-Cyanine5.5, is specifically designed for flow cytometry applications, providing high sensitivity and specificity in detecting and analyzing human CD18 expression in various cell types.CD18, a subunit of the β2 integrin family, plays a crucial role in mediating immune responses, including leukocyte adhesion and migration. By targeting CD18, researchers can gain insights into the mechanisms underlying immune cell interactions and inflammatory processes.
This antibody facilitates the visualization and quantification of CD18 expression levels, making it a valuable tool for studies in immunology, inflammation, and autoimmune diseases.With its validated performance in flow cytometry, the Human CD18 Monoclonal Antibody (PE-Cyanine5.5 Conjugated) - TS1/18, 1-2-11 (AGEL0983) from AssayGenie enables precise and reliable analysis of CD18 expression, making it an essential reagent for researchers investigating the role of CD18 in immune responses and inflammatory conditions.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P05107
Gene ID:
3689
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD18 is a 90-95 kD type I transmembrane protein also known as integrin β2 subunit, LFA-1 β subunit, and β2 integrin. CD18 non-covalently associates with CD11a, CD11b or CD11c. CD18 is expressed on all leukocytes. CD18 and associated α chains function in adhesion and signaling in hematopoietic cells.