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PE Anti-Human CD161 Antibody [HP-3G10] (AGEL1792)

SKU:
AGEL1792
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
€219 - €709
Frequently bought together:

Description

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PE Anti-Human CD161 Antibody [HP-3G10]

The Human CD161 Monoclonal Antibody (PE-conjugated, HP-3G10) is a cutting-edge tool for researchers investigating CD161, a cell surface marker associated with immune function and natural killer (NK) cells. This antibody is specifically designed to target and detect the CD161 protein in human samples, providing valuable insights into its expression and localization.CD161, also known as NKR-P1A, is a marker commonly found on NK cells and subsets of T cells, playing a key role in immune responses and cell-mediated cytotoxicity. Its expression is linked to various immune processes, making it a crucial target for studies in immunology and infectious diseases. The PE-conjugated HP-3G10 antibody allows for precise detection of CD161, facilitating detailed analysis of its function in different cell populations.

Researchers can utilize this antibody in flow cytometry and immunofluorescence experiments to investigate the presence and distribution of CD161 in various immune cell subsets. By understanding the role of CD161 in immune surveillance and response, scientists can further unravel its implications in conditions such as viral infections, autoimmune diseases, and cancer.With its high specificity and reliable performance, the Human CD161 Monoclonal Antibody (PE-conjugated, HP-3G10) from AssayGenie is a valuable tool for advancing research in immunology, oncology, and infectious diseases.

Product Title:PE Anti-Human CD161 Antibody [HP-3G10]
SKU:AGEL1792
Size:20 Tests, 100 Tests, 200 Tests
Clone No:HP-3G10
Synonyms:CLEC5B; NKRP1A;NKR-P1A;HNKR-P1a;KLRB1;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q12918
Gene ID:3820
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD161 is a type II transmembrane glycoprotein, also known as NKR-P1A, that is expressed as a 40-44 kD homodimer. It is a member of the C-type lectin superfamily. CD161 is expressed on a majority of NK cells, NKT cells, and subsets of peripheral T cells and CD3+ thymocytes. It has been reported that Th17 cells are a subpopulation of CD4+CD161+CCR6+ cells. While the biological function of CD161 is not clear, it has been suggested to serve either as a stimulatory receptor or to inhibit NK cell-mediated cytotoxicity and cytokine production. LLT-1 (lectin-like transcript-1, also named as osteoclast inhibitory lectin or CLEC2D) is the ligand of CD161.

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