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FITC Anti-Human CD161 Antibody [HP-3G10] (AGEL1791)

SKU:
AGEL1791
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
$263 - $851
Frequently bought together:

Description

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FITC Anti-Human CD161 Antibody [HP-3G10]

The Human CD161 Monoclonal Antibody (FITC Conjugated, HP-3G10) is a vital tool for researchers studying CD161, a cell surface marker associated with certain populations of T cells. This monoclonal antibody, conjugated with FITC for fluorescent detection, offers high specificity and sensitivity when detecting CD161 in human samples. Validated for use in flow cytometry applications, this antibody binds specifically to the CD161 protein, facilitating its detection and analysis in diverse cell types.CD161, also known as NKR-P1A, is a marker of certain immune cell subsets, including natural killer cells and subsets of T cells. Understanding the expression and function of CD161 is important in immunology research, particularly in studies focusing on immune cell populations and their role in various physiological and pathological conditions.

The CD161 monoclonal antibody supports investigations into immune cell function and behavior, making it a valuable asset in research areas such as immunology, infectious diseases, and autoimmune disorders.Overall, the Human CD161 Monoclonal Antibody (FITC Conjugated, HP-3G10) provides researchers with a reliable tool for the detection and analysis of CD161-expressing cells, aiding in the advancement of knowledge in the field of immunology and related research disciplines.

Product Title:FITC Anti-Human CD161 Antibody [HP-3G10]
SKU:AGEL1791
Size:20 Tests, 100 Tests, 200 Tests
Clone No:HP-3G10
Synonyms:CLEC5B; NKRP1A;NKR-P1A;HNKR-P1a;KLRB1;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:FITC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q12918
Gene ID:3820
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD161 is a type II transmembrane glycoprotein, also known as NKR-P1A, that is expressed as a 40-44 kD homodimer. It is a member of the C-type lectin superfamily. CD161 is expressed on a majority of NK cells, NKT cells, and subsets of peripheral T cells and CD3+ thymocytes. It has been reported that Th17 cells are a subpopulation of CD4+CD161+CCR6+ cells. While the biological function of CD161 is not clear, it has been suggested to serve either as a stimulatory receptor or to inhibit NK cell-mediated cytotoxicity and cytokine production. LLT-1 (lectin-like transcript-1, also named as osteoclast inhibitory lectin or CLEC2D) is the ligand of CD161.

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