The Human CD147 Monoclonal Antibody (PE Conjugated) - HIM6 (AGEL0971) is a high-quality antibody designed for research purposes involving the CD147 protein, also known as EMMPRIN or basigin. CD147 is a cell surface glycoprotein that plays a crucial role in various physiological and pathological processes, including tumor invasion, metastasis, inflammation, and immune response modulation.This monoclonal antibody, conjugated with PE (phycoerythrin), is specifically engineered for use in flow cytometry applications for the detection and analysis of CD147 expression on the surface of human cells. It offers high specificity and sensitivity, allowing researchers to accurately study the distribution and function of CD147 in different cell types and biological contexts.The HIM6 antibody is rigorously validated and has demonstrated excellent performance in flow cytometry experiments, providing reliable results for researchers studying CD147-related pathways and mechanisms.
By targeting the CD147 protein, this antibody enables detailed investigations into the role of CD147 in disease processes such as cancer progression, inflammation, and immune modulation.Overall, the Human CD147 Monoclonal Antibody (PE Conjugated) - HIM6 (AGEL0971) serves as a valuable tool for researchers interested in elucidating the functions of CD147 and its implications in various diseases and biological processes. Its high specificity, conjugated format, and reliable performance make it an essential component in studies focused on understanding the role of CD147 in human health and disease.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P35613
Gene ID:
682
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD147, also known as neurothelin or basigin, is a member of the Ig superfamily. It is a 55-65 kD type I transmembrane glycoprotein which is primarily expressed on leukocytes, erythrocytes, platelets, and endothelial cells. CD147 is reported to have a function during embryonal brain development and/or play a role in integrin-mediated adhesion in brain endothelia.