The Human CD147 Monoclonal Antibody (HIM6) is a cutting-edge tool for researchers investigating CD147, a multifunctional glycoprotein involved in various physiological and pathological processes. This monoclonal antibody, designated HIM6 and available from AssayGenie, is specifically designed for use in studies related to CD147 expression and function.By targeting the CD147 protein with high specificity, the HIM6 monoclonal antibody enables precise detection and analysis in a wide range of human samples. Validated for applications such as Western blotting, immunofluorescence, and flow cytometry, this antibody provides researchers with a robust tool for investigating the role of CD147 in diverse cellular contexts.CD147, also known as Basigin or EMMPRIN, plays pivotal roles in processes such as cell adhesion, proliferation, and migration, making it a key player in cancer progression, inflammation, and tissue remodeling.
By utilizing the HIM6 monoclonal antibody, researchers can delve deeper into the mechanisms by which CD147 influences these processes, facilitating advancements in cancer biology, immunology, and therapeutic development.As CD147 continues to emerge as a promising therapeutic target in various diseases, the HIM6 monoclonal antibody serves as a crucial asset for researchers seeking to unravel the complexities of CD147 biology and its implications in human health and disease. Trust in the HIM6 monoclonal antibody to drive your research forward and unlock new insights into the roles of CD147 in physiology and pathology.
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD147, also known as neurothelin or basigin, is a member of the Ig superfamily. It is a 55-65 kD type I transmembrane glycoprotein which is primarily expressed on leukocytes, erythrocytes, platelets, and endothelial cells. CD147 is reported to have a function during embryonal brain development and/or play a role in integrin-mediated adhesion in brain endothelia.