The Human CD147 Monoclonal Antibody (APC Conjugated) HIM6 (AGEL0972) offered by Assay Genie is a cutting-edge tool designed for research in the field of immunology and cell biology. This monoclonal antibody is specifically engineered to target CD147, a transmembrane glycoprotein involved in various physiological and pathological processes.This advanced antibody, conjugated with APC for enhanced detection capabilities, is meticulously validated for its reactivity with human samples. Its high specificity and sensitivity make it an ideal choice for applications such as flow cytometry, immunofluorescence, and immunohistochemistry.CD147, also known as extracellular matrix metalloproteinase inducer (EMMPRIN), is recognized for its roles in cell adhesion, migration, and invasion, as well as its involvement in diverse diseases including cancer and inflammatory disorders.
By targeting CD147, researchers can gain valuable insights into the mechanisms underlying these conditions and potentially identify novel therapeutic strategies.With its proven performance and versatility, the Human CD147 Monoclonal Antibody (APC Conjugated) HIM6 (AGEL0972) from Assay Genie is a powerful tool for unraveling the complexities of CD147 biology and advancing scientific discoveries in a wide range of research areas.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P35613
Gene ID:
682
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD147, also known as neurothelin or basigin, is a member of the Ig superfamily. It is a 55-65 kD type I transmembrane glycoprotein which is primarily expressed on leukocytes, erythrocytes, platelets, and endothelial cells. CD147 is reported to have a function during embryonal brain development and/or play a role in integrin-mediated adhesion in brain endothelia.