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GenieFluor 488 Anti-Human CD147 Antibody [HIM6] (AGEL0978)

SKU:
AGEL0978
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2a,k
Clone:
HIM6
Conjugation:
AF 488
€209 - €709
Frequently bought together:

Description

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GenieFluor 488 Anti-Human CD147 Antibody [HIM6]

The Human CD147 Monoclonal Antibody (AF488 Conjugated) (HIM6) is a cutting-edge tool for researchers studying CD147, a transmembrane glycoprotein that plays a crucial role in various physiological and pathological processes. This monoclonal antibody, conjugated with AF488 for fluorescence-based detection, offers high specificity and sensitivity in detecting CD147 in human samples.CD147, also known as extracellular matrix metalloproteinase inducer (EMMPRIN), is involved in diverse cellular functions such as cell adhesion, migration, and proliferation. Its overexpression has been linked to inflammation, tumor progression, and metastasis, making it a promising therapeutic target in cancer research and immunology.

The HIM6 antibody provides researchers with a reliable tool for visualizing and quantifying CD147 expression in different cell types and tissues through imaging techniques like immunofluorescence and flow cytometry. By elucidating the role of CD147 in various diseases, including cancer and inflammatory conditions, this antibody contributes to advancing our understanding of disease mechanisms and identifying potential treatment avenues.Overall, the Human CD147 Monoclonal Antibody (AF488 Conjugated) (HIM6) from AssayGenie is a valuable resource for scientists seeking to explore the functions and implications of CD147 in health and disease, paving the way for innovative research and therapeutic development.

Product Title:GenieFluor 488 Anti-Human CD147 Antibody [HIM6]
SKU:AGEL0978
Size:20 Tests, 100 Tests, 200 Tests
Clone No:HIM6
Synonyms:Basigin;BSG;5F7;Collagenase stimulatory factor;Extracellular matrix metalloproteinase inducer;EMMPRIN;Leukocyte activation antigen M6;OK blood group antigen;Tumor cell-derived collagenase stimulatory factor;TCSF;CD147;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Genie Fluor 488 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P35613
Gene ID:682
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD147, also known as neurothelin or basigin, is a member of the Ig superfamily. It is a 55-65 kD type I transmembrane glycoprotein which is primarily expressed on leukocytes, erythrocytes, platelets, and endothelial cells. CD147 is reported to have a function during embryonal brain development and/or play a role in integrin-mediated adhesion in brain endothelia.

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