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FITC Anti-Human CD127/IL-7RA Antibody [A019D5] (AGEL1782)

SKU:
AGEL1782
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2a,k
Clone:
A019D5
Conjugation:
FITC
€219 - €709
Frequently bought together:

Description

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FITC Anti-Human CD127/IL-7RA Antibody [A019D5]

The Human CD127 (IL-7RA) Monoclonal Antibody (AGEL1782) offered by Assay Genie is an essential tool for researchers studying CD127, a crucial cell surface receptor involved in immune function. This FITC-conjugated monoclonal antibody is specifically designed for use in flow cytometry applications, enabling the detection and analysis of CD127 in human samples with high precision and sensitivity.CD127, also known as IL-7RA, plays a key role in the development and maintenance of immune cells, particularly T cells. By targeting CD127, researchers can gain insights into the regulation of T cell differentiation, survival, and proliferation, essential for understanding immune responses in various contexts. The use of this monoclonal antibody allows for detailed studies into the expression pattern and function of CD127 in different cell populations, making it a valuable tool for immunology and cancer research.

By exploring the role of CD127 in immune regulation, researchers can uncover new therapeutic targets for conditions such as autoimmune diseases, infectious diseases, and cancer. The precise binding ability of this monoclonal antibody offers researchers the opportunity to explore the intricate mechanisms of CD127 signaling pathways, shedding light on the potential for novel treatment strategies. With its high specificity and superior performance in flow cytometry experiments, the Human CD127 (IL-7RA) Monoclonal Antibody from Assay Genie is a valuable asset for advancing research in immunology and beyond.

Product Title:FITC Anti-Human CD127/IL-7RA Antibody [A019D5]
SKU:AGEL1782
Size:20 Tests, 100 Tests, 200 Tests
Clone No:A019D5
Synonyms:Interleukin-7 receptor subunit alpha;IL-7RA;CDw127;CD127;IL-7Rα;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:FITC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P16871
Gene ID:3575
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage cells, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be a useful marker for identifying memory and effector T cells. Studies have shown that CD127 expression is down-modulated on Treg cells. It can be used as a marker for differentiation of Treg and conventional T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cell proliferation and development.

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