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PE/Cyanine5 Anti-Human CD123 Antibody [6H6] (AGEL1458)

SKU:
AGEL1458
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
$263 - $851
Frequently bought together:

Description

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PE/Cyanine5 Anti-Human CD123 Antibody [6H6]

The Human CD123 Monoclonal Antibody PE-Cyanine5 Conjugated (6H6) is a cutting-edge tool for researchers studying CD123, a cell surface marker closely associated with hematopoietic stem and progenitor cells. This monoclonal antibody, conjugated with PE-Cyanine5, offers high specificity and sensitivity for human samples, making it a reliable choice for flow cytometry and immunophenotyping experiments. CD123, also known as interleukin-3 receptor alpha chain, plays a pivotal role in hematopoiesis and is a crucial target in the diagnosis and treatment of hematologic malignancies, particularly acute myeloid leukemia and myelodysplastic syndromes. By facilitating the identification and characterization of CD123-expressing cells, this antibody enables researchers to delve deeper into the mechanisms underlying leukemogenesis and to explore potential therapeutic strategies targeting CD123-positive cells.

With its robust performance and applicability in a range of experimental settings, the Human CD123 Monoclonal Antibody PE-Cyanine5 Conjugated (6H6) is a valuable asset for investigations in the fields of hematology, oncology, and immunology. Unlock the potential of CD123 research with this innovative antibody and advance your understanding of hematopoietic disorders and immune-related diseases.

Product Title:PE/Cyanine5 Anti-Human CD123 Antibody [6H6]
SKU:AGEL1458
Size:20 Tests, 100 Tests, 200 Tests
Clone No:6H6
Synonyms:IL-3Rα; IL-3 Receptor alpha;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P26951
Gene ID:3563
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD123 is the 70 kD transmembrane α chain of the IL-3 receptor. Alone, CD123 binds IL-3 with low affinity; when CD123 associates with CDw131 (common β chain), it binds IL-3 with high affinity. CD123 does not transduce intracellular signals upon binding IL-3 and requires the β chain for this function. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and some B cells.

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