null

GenieFluor 647 Anti-Human CD123 Antibody [6H6] (AGEL1460)

SKU:
AGEL1460
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
€219 - €709
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

GenieFluor 647 Anti-Human CD123 Antibody [6H6]

The Human CD123 Monoclonal Antibody (AF647 Conjugated, 6H6) is a cutting-edge research tool designed for the study of CD123, a cell surface protein involved in immune function and hematopoiesis. This antibody, derived from mouse monoclonal sources, exhibits high specificity and sensitivity for detecting CD123 in human samples, particularly when used in flow cytometry and immunofluorescence applications.CD123, also known as interleukin-3 receptor alpha chain, is a crucial biomarker in the field of hematology and immunology, playing a key role in the development and differentiation of various immune cells, including dendritic cells and basophils.

Its overexpression has been linked to certain hematological malignancies, making it a promising target for therapeutic interventions and diagnostic purposes in conditions like acute myeloid leukemia (AML).By utilizing the Human CD123 Monoclonal Antibody (AF647 Conjugated, 6H6), researchers can gain valuable insights into the role of CD123 in normal and pathological immune responses, paving the way for advancements in cancer therapy, immunotherapy, and other areas of biomedical research. Unlock the potential of CD123 in your studies with this powerful and reliable antibody tool.

Product Title:GenieFluor 647 Anti-Human CD123 Antibody [6H6]
SKU:AGEL1460
Size:20 Tests, 100 Tests, 200 Tests
Clone No:6H6
Synonyms:IL-3Rα; IL-3 Receptor alpha;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Genie Fluor 647 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P26951
Gene ID:3563
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD123 is the 70 kD transmembrane α chain of the IL-3 receptor. Alone, CD123 binds IL-3 with low affinity; when CD123 associates with CDw131 (common β chain), it binds IL-3 with high affinity. CD123 does not transduce intracellular signals upon binding IL-3 and requires the β chain for this function. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and some B cells.

Related Products